Dr. Jean Suffert Research Group

Our research group is located in the Faculty of Pharmacy in Strasbourg (France) and is a part of the Laboratory for Therapeutic Innovation (UMR CNRS/UDS 7200). Different groups compose this laboratory and each have their own scientific skills, such as organic synthesis, medicinal chemistry, molecular modeling, pharmacognosy and pharmacology, resulting in an academic plateform that can focus its research on a better understanding of cellular communication in living systems.

In addition, the University of Strasbourg is offering an unique and stimulating environment as it ranks 16th in the world for chemistry (ARWU ranking)

Our group is one of the teams constituting the International Center for Frontier Research in Chemistry (ICFRC).
In 2007, the French Government selected Strasbourg as the Center of Excellence in Chemistry for the country. ICFRC involves 80 teams in different institutes in Strasbourg comprising about 250 scientists and faculty members, 250 PhD students and 250 post-docs and technical staff.

Our team aim is to explore and provide new synthetic tools for the manufacturing of biomolecules. Our areas of interest include diastereoselectives reactions, multicomponante reactions, 1,3 dipolar species, heterocyclic chemistry, palladium chemistry, cascade/domino reactions, synthesis of complexes molecules, enediynes, anticancer agents.

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Funded by :


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anr

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AAREC
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News   (archives)

17.11.2014 : PhD Student Workshop (AMT)
A workshop on total synthesis and bioactive molecules will take place at the faculty of pharmacy with prestigious speakers: Pr. Zhu from EPFL (CH), Pr. Bruckner from Freiburg im Breisgau (D) and Pr. Compain from Strasbourg

10.07.2014 : New Chem. Comm. has been accepted!!!
Congratulations to Pierre, Jean-François, André, Jean, Marcel, Nicolas and Dominique for their paper about a new domino process to reach distereoselectively novel Aza-Diketopiperazines.

11.06.2014 : Our soccer team has won (once again!!) the chemistry department championship!!!  Well done guys!!!!!!

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01.05.2014 : New Org. Lett. has been accepted!!!
Congratulations to Thomas, Morgan, Mihaela and Jean for their paper about cascade reactions on sulfured substrates which has been accepted in Organic Letters.

Available Position(s)

No available position at the present time. However, spontaneous applications are welcome : visit our "opportunities" webpage

Selected Recent Publications

Chem. Commun., 2014, 50 , 9657
Diastereoselective Synthesis of Novel Azadiketopiperazines via a Domino Cyclohydrocarbonylation/Addition Process

Org. Lett., 2014, 16, 3060
Cyclocarbopalladation/Cross-Coupling Cascade Reactions in Sulfide Series: Access to Sulfur Heterocycles

Eur. J. Med. Chem., 2014, 74, 41
Benzofuran derivatives as a novel class of inhibitors of mTOR signaling

Angewandte Chemie int. Ed., 2013, 52, 12786
Fenestranes in Synthesis: Unique and Highly Inspiring Scaffolds
 
Tetrahedron, 2013, 69, 7568
Expeditious cascade reactions: controlled syntheses of fenestradienes and cyclooctatrienes under palladium catalysis

Angewandte Chemie int. Ed. 2012, 51, 4379
An Expeditious and Atom-Economical Synthesis of a New Generation of Substituted [4.6.4.6]Fenestradienes.